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Liquid Biopsy

Revolutionising Non-Invasive Diagnostics with the Lynx System

 

At Dynamic Bio-Solutions, we are transforming the landscape of non-invasive diagnostics with our Lynx system. This cutting-edge technology empowers healthcare providers in the UK and MEA regions to perform liquid biopsy—a non-invasive method for cancer detection, treatment monitoring, and recurrence detection—faster, more accurately, and with greater flexibility than ever before.


Liquid biopsy has quickly emerged as a game-changing tool in oncology, enabling clinicians to detect cancer-related biomarkers from a simple blood sample, reducing patient risk and enabling earlier detection of malignancies. To support this revolution, the Lynx system delivers the precision, speed, and automation needed to make liquid biopsy a reality across clinical setting

What is Liquid Biopsy?

 Liquid biopsy is an innovative, non-invasive diagnostic tool that allows the detection of cancer biomarkers from bodily fluids, especially blood. Unlike traditional biopsies, liquid biopsies offer a safer and quicker way to monitor and detect cancer at early stages, providing patients with better outcomes through earlier intervention. 

How Liquid Biopsy Works:

 

  • Detection: Liquid biopsy captures genetic mutations and biomarkers related to cancer from a blood sample, making it possible to identify cancer before symptoms appear.
  • Monitoring: It tracks changes in biomarkers over time, allowing clinicians to monitor treatment effectiveness and detect the recurrence of cancer at the earliest stage.

Why Choose the Lynx System for Liquid Biopsy?

Exclusive 24-Channel 5mL Pipetting Tool

 

  • Lynx is the only system to offer 24 independent pipetting channels using 5mL disposable tips. This capability allows you to handle large-volume liquid biopsy samples (up to 5,000 μL/channel) with unmatched efficiency. Whether you're working with blood samples, ctDNA, or magnetic bead-based extractions, this feature significantly speeds up workflows while maintaining accuracy.
  • Most other systems on the market offer higher channel counts, but none provide the volume flexibility of the Lynx system's 24-channel 5mL pipetting tool. With Lynx, you can process larger volumes in a single pass, reducing the need to split samples, and improving both throughput and efficiency.

Optimised for Liquid Biopsy

 

  • The Lynx system integrates magnetic bead handling for liquid biopsy workflows, such as circulating tumour DNA (ctDNA) isolation, directly into the system. This seamless integration reduces the complexity of manual interventions, replacing cumbersome external systems, and enabling you to conduct the entire liquid biopsy workflow on a single platform.
  • From sample processing to pipetting, the Lynx system ensures that every step is optimised for liquid biopsy, allowing labs to scale non-invasive testing seamlessly, especially in high-throughput environments.

High-Throughput & Flexibility

 

  • With the Lynx system, you can perform high-throughput liquid biopsy workflows that can handle a variety of sample types and test protocols. The Lynx features versatile tools such as the 96VVP Pipetting Tool and 24VVP Pipetting Tool, which enable simultaneous processing of multiple samples while maintaining flexibility across various applications, including serial dilutions, normalisation, and hit picking.
  • Unlike traditional systems, which are often limited in their ability to handle large volumes or more complex workflows, Lynx provides the flexibility to tailor your system to the unique needs of your lab, regardless of sample size or test complexity.

Cost-Effective and Superior Performance

 

  • The Lynx system offers significant cost savings compared to other systems on the market that offer similar features but at higher operational costs. For example, while some competitors require additional external devices for sample processing, Lynx consolidates the entire workflow into one efficient platform, reducing equipment costs and lowering overall system maintenance.
  • The Lynx system's advanced automation and precision ensure superior performance, and it has been validated in real-world clinical environments, ensuring that it meets the rigorous demands of liquid biopsy diagnostics.

Full Automation and Walkaway Capability

 

  • The Lynx system offers significant cost savings compared to other systems on the market that offer similar features but at higher operational costs. For example, while some competitors require additional external devices for sample processing, Lynx consolidates the entire workflow into one efficient platform, reducing equipment costs and lowering overall system maintenance.
  • The Lynx system's advanced automation and precision ensure superior performance, and it has been validated in real-world clinical environments, ensuring that it meets the rigorous demands of liquid biopsy diagnostics.

Workflow Efficiency and Results

 In collaboration with Omega Bio-tek, this automated system uses the Lynx LM1200 platform and 24ST Pipetting Tool, coupled with Omega Bio-tek’s Mag-Bind® cfDNA Kit, to handle 24 x 10 mL plasma samples in 65 minutes. The automated workflow enables high-volume cfDNA extraction without the need for sample splitting, offering an efficient solution for high-throughput labs.

  • High Yield and Purity: Automated extraction using this system has been shown to produce cfDNA yields comparable to manual methods, with minimal inhibitors and high purity, making it ideal for quantitative PCR and other downstream analysis methods.

Lynx System Features for Liquid Biopsy Workflows:

 

  • 96VVP Pipetting Tool: Handles 96 independent volumes with real-time monitoring and verification, ideal for high-throughput liquid biopsy workflows.


  • 24VVP Pipetting Tool: The only system to offer 24 independent 5mL volumes, perfect for large-volume DNA extraction and liquid biopsy sample distribution.


  • iMagZ Magnetic Bead Processing: On-deck processing for high-throughput bead binding and elution in 96, 24, and 6-well formats.


  • Customisable Pipetting Schemes: Dynamic pipetting protocols for precise mixing, serial dilutions, and normalisation tasks.


  • Real-Time Volume Verification: Ensures accuracy in every liquid transfer, minimising error rates in critical diagnostic workflows.

Applications of the 24-Channel 5 mL Pipetting System:

 

  • Oncology Diagnostics: The system is ideal for liquid biopsy workflows, offering high-volume processing to detect circulating tumour DNA (ctDNA), making it essential for early cancer detection and monitoring cancer progression.
  • Genomic Testing: The system’s capacity for high-volume blood processing makes it suitable for genomic sequencing and genetic screening, particularly for non-invasive prenatal testing (NIPT) and infectious disease diagnosis.
  • Minimal Residual Disease Monitoring: Use the system to track minimal residual disease (MRD) by efficiently extracting sufficient cfDNA from blood plasma samples.




 

Conclusions

The 24-Channel 5 mL Pipetting System offers a robust and automated solution for cfDNA extraction from high-volume plasma samples, streamlining the process for liquid biopsy workflows. By eliminating the need for sample splitting and processing up to 10 mL of plasma per sample in one run, this system delivers faster, more accurate, and high-throughput results, making it an essential tool for oncology diagnostics, genomic testing, and non-invasive disease monitoring.

Get Started with the Lynx System Today

 

At Dynamic Bio-Solutions, we are committed to helping healthcare providers in the UK and MEA regions streamline their liquid biopsy workflows. Our Lynx system offers the flexibility, speed, and precision needed to bring non-invasive diagnostics to the forefront of cancer care.

Request a demo today to see how the Lynx system can enhance your lab’s liquid biopsy capabilities and transform the way you perform cancer diagnostics. Whether you’re focused on early cancer detection, monitoring treatment efficacy, or detecting recurrence, Lynx is your trusted partner in making non-invasive testing a reliable reality.

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124 City Road, London, United Kingdom, EC1V 2NX

+44 (0) 7874 267 183

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