VVP: Volume Verified Pipetting

• Superior flexibility for 96 & 24-channel automated liquid handling
• Expands pipetting workflow efficiency by several-fold over traditional tools
• Perform plate normalizations, serial dilutions & other common routines in record time

• Ultimate pipetting confidence with real-time volume verification
• Removes the guesswork from automated liquid handling once-and-for-all
• Any liquid, at any volume…with zero liquid class development

• New levels of process security with continuous QC monitoring of all channels
• More robust workflows with advanced user-defined recovery for ‘on-the-fly’ corrections
• Final validation data report captures all pipetting data

Independent-channel LLD on all liquid types is performed via controlled micro-releases of air from the distal end of the tip and subsequent monitoring of pressure changes associated with meniscus (or bubble/foam) interference. A residual volume based on the confirmed meniscus height and labware definition is calculated. Any pipetting discrepancies experienced are addressed via several user-defined error recovery options.

Air-based VVP technology accomplishes robust LLD without the need for more expensive carbon-impregnated (capacitance-based LLD) disposable tips. For the best pipetting results, be sure to use D2-brand ‘performance-certified’ clear disposable tips.

VVP performs continuous millisecond analysis of flow rates for each liquid channel. A disruption in the expected average flow rate, produced either by air entering the channel (i.e. ‘short or no sample’) or a blockage (i.e. clot/clog) triggers an alert.

Diagnosed pipetting errors are addressed automatically ‘on-the-fly’ via user-defined error recovery options.

Independent control of each channel affords the freedom to isolate and disable only the offending channel(s), allowing the method to continue without interruption.

Upon method completion, a final Error Report file is generated.