Next-Generation Sequencing

 Lynx integrates VVP technology, ensuring real-time volume verification for every pipetting action. Each transfer is monitored and adjusted in real-time, guaranteeing error-free pipetting and consistent, reliable results.

With 96 independent channels, Lynx can handle varying sample volumes and ensure precise transfers, eliminating the need for manual pipetting and reducing variability. This precision is critical for NGS library prep, where even small pipetting errors can affect sequencing results.

 Head Configurations: The MCPA option offers incredible versatility, with the ability to switch between different pipetting heads—from dual heads to the 5mL head and the 96 VVP head—to suit various NGS library prep steps.With real-time volume verification and independent control for each channel, Lynx ensures error-free pipetting for every sample. Every step, from adapter ligation to sample pooling, is carried out with complete accuracy, ensuring the highest quality sequencing libraries.

 96 VVP Head: This head is designed for high-throughput NGS workflows. 

It processes 96-well plates and can easily pipette into 384-well plates without recalibration. This means that whether you are running single plates or handling high-density plates, Lynx adapts instantly to meet your needs—perfect for sample pooling, serial dilutions, and normalisation in NGS prep. 

• Dual Head: Available on the LM1800 and LM1200 models, the dual head configuration allows for greater flexibility when handling larger volumes or when precision across multiple plates is required. This dual head system ensures parallel pipetting for higher throughput, ideal for complex NGS prep workflows.
• 24 channel 5mL Tips: Perfect for handling large volume transfers or more complex NGS prep workflows, this head can handle up to 5mL per channel, ideal for NGS workflows that require flexibility for varying volumes or applications such as high-throughput sequencing.

 In an NGS library prep protocol, several critical steps benefit from Lynx's scalability:

1. Sample Normalisation:
   Using the 96 VVP head (or FlexTrough with MCPA), Lynx normalises sample volumes in less than 45 seconds for 96-well plates, speeding up this step dramatically. Whether you are processing small-scale libraries or running large genomic studies, Lynx delivers consistent normalisation—without recalibration, even when switching between 96-well and 384-well plates.

The 96 VVP head enables efficient pooling of samples, reducing the number of pipetting motions required. The system handles the full workload with minimal user input, ensuring faster sample handling and reduced error rates—critical when pooling hundreds or even thousands of samples for high-throughput sequencing. 

Lynx excels at serial dilutions with real-time volume verification. The system can perform complex dilutions across multiple plates with 96 independent channels—ensuring that the results are precise and repeatable, even when scaling up to higher volumes or varying concentrations.